Our expertiseNervous system

Nervous system & stress

The nervous system governs how the body responds to demand, recovers from strain and maintains balance. Chronic stress is not just a state of mind. It has measurable biological consequences across almost every system in the body.
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Why Nervous system &
stress matters

The stress response is designed to be temporary. When it becomes chronic, the body pays a significant price. Elevated cortisol over time suppresses immunity, disrupts hormonal balance, impairs gut function and affects sleep, memory and mood.

We work with people who have been managing stress for years without anyone looking at what it is doing to their biology.

Concerns where
Nervous system & stress
may play a role

Together with Dr Fiona Forbes and the medical team, we use over 400 biomarkers to understand the underlying factors contributing to symptoms.

BurnoutChronic stressAnxietyLow moodBurnoutChronic stressAnxietyLow mood
FatiguePoor sleepBrain fogDifficulty concentratingFatiguePoor sleepBrain fogDifficulty concentrating
Low resilienceAdrenal fatigueCortisol dysregulationIrritabilityLow resilienceAdrenal fatigueCortisol dysregulationIrritability
Emotional dysregulationPoor recoveryTinnitusTension headachesEmotional dysregulationPoor recoveryTinnitusTension headaches
Loss of motivationLoss of motivation

These concerns are not assessed in isolation, but always in the context of the full biological picture.

How nervous system & stress
connects to other systems

Chronic stress and nervous system dysregulation rarely stay contained to one area.

Elevated cortisol suppresses sex hormone production and disrupts thyroid function
Adrenal dysregulation affects blood sugar regulation and energy metabolism
Chronic stress compromises gut lining integrity and microbiome balance
Sleep disruption from nervous system dysregulation impairs immune function and recovery
Prolonged stress accelerates biological ageing and cellular damage

Our approach

At Forbes.health, we assess the nervous system and stress response through biomarkers that show what chronic stress is actually doing to the body. That includes cortisol patterns, adrenal function, neurotransmitter markers and the downstream effects on other systems.

We look at the biological picture behind the burnout, not just the symptoms.

Our role is not only to identify what is out of range, but to understand how the body is functioning as a whole, and what may be driving symptoms beneath the surface.

Dr Fiona Forbes

Dr Fiona Forbes,

Chief Medical Officer

How we assess

Relevant testing panels

The most relevant tests depend on the individual, their symptoms and their medical history. For nervous system & stress, the following panels are frequently used:

Stress and Hormone Panel (SHP)

Measures cortisol patterns across the day including morning peak, daytime rhythm and evening levels, alongside DHEAS and sex hormones. Reveals how the body is managing and recovering from stress. One of the most important panels for anyone dealing with burnout or adrenal concerns.

Organic Acids Test (OAT)

Includes neurotransmitter metabolites such as serotonin, dopamine and GABA markers. Adds important context where stress overlaps with mood, sleep and cognitive function. Also assesses nutritional cofactors that support nervous system function.

Thyroid Panel Plus Hormones and PSA

Thyroid dysfunction frequently accompanies chronic stress and cortisol dysregulation. We include this panel where thyroid-related patterns are present alongside stress symptoms.

Oxidative Stress Panel

Chronic stress generates significant oxidative damage at a cellular level. This panel measures DNA damage markers and the body's antioxidant capacity, showing how much of a toll prolonged stress is taking on the body's cells.

From insight to direction

Whether navigating persistent symptoms or taking a proactive approach, the goal is always the same: to understand what your body is doing and why.

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Questions and answers

Frequently asked questions

Adrenal fatigue describes a pattern of symptoms linked to dysregulated cortisol output. The underlying biological patterns are measurable. We test cortisol rhythm directly, across multiple points in the day, rather than relying on a single reading.

Yes. A single cortisol reading tells you very little. Cortisol follows a daily rhythm, and the pattern matters as much as the level. We measure multiple points across the day to understand the full picture.

Burnout has measurable biological correlates including cortisol dysregulation, immune suppression and hormonal disruption. While it is not a formal diagnosis, the biological consequences are real and testable. We treat it as a biological state, not just a psychological one.

Therapy addresses psychological patterns. We address the biological underpinning of how the body is responding to stress. The two are complementary. We do not replace psychological care, but we often identify biological factors that make recovery more difficult even when other support is in place.